SOPHiA DDM™ Platform

One platform, endless possibilities
A cutting-edge, cloud-native SaaS IVDR-certified* platform for the accurate analysis, standardization, and interpretation of complex healthcare data. Our advanced AI algorithms are breaking data siloes and democratizing access to anonymized real-world insights.
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*When used in Dx mode.
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CUMIN™: Precise molecular barcoding

SOPHiA DDM™ enables sensitive detection of clinically relevant variants at low allele frequencies (< 0.01% VAF) for MRD.
By incorporating our proprietary CUMIN™ unique molecular identifier (UMI) technology into sample preparation and leveraging our bioinformatic expertise, errors introduced during library preparation, target enrichment, or sequencing can be filtered out and true variant alleles identified.
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Enhance your clinical research programs with exploratory and testing

Identifying the specific molecular profiles of the target population for your clinical research program in an accurate, consistent, and standardized way can hinder your development process.
By applying our expertise in genomics and sophisticated algorithms, we help you discover, prioritize, and select the most promising biomarker targets for your clinical research program.

CUMIN™: Precise molecular barcoding

SOPHiA DDM™ enables sensitive detection of clinically relevant variants at low allele frequencies (< 0.01% VAF) for MRD.
By incorporating our proprietary CUMIN™ unique molecular identifier (UMI) technology into sample preparation and leveraging our bioinformatic expertise, errors introduced during library preparation, target enrichment, or sequencing can be filtered out and true variant alleles identified.

Test  CUMIN™: Precise molecular barcoding

SOPHiA DDM™ enables sensitive detection of clinically relevant variants at low allele frequencies (< 0.01% VAF) for MRD.
By incorporating our proprietary CUMIN™ unique molecular identifier (UMI) technology into sample preparation and leveraging our bioinformatic expertise, errors introduced during library preparation, target enrichment, or sequencing can be filtered out and true variant alleles identified.

Conquer new summits in data-driven medicine

Best-in-class accuracy
Using robust AI-powered algorithms to pinpoint signals amongst noise for actionable insights.
Expedited turnaround
Harness a comprehensive platform to quickly gather and analyze multiple data types.
Accelerated adoption
Leverage our expertise to easily integrate and scale up the right application for your institution.
Optimized resources
Save time and control costs on data processing and storage with our scalable infrastructure.
Full data control
Confidently generate data in-house while securely maintaining full control over your samples and data.

A connected community for collective intelligence

SOPHiA DDM™ – Universally compatible, infinitely powerful

Accurate
AI/machine learning-powered algorithms accurately, analyze, standardize, and annotate data for confident decision making.
Universal
The technology-agnostic platform easily integrates into existing workflows, supporting diverse data types and applications.
Decentralized

Enabling in-house data analysis empowers institutions to maintain full control of their samples and data.

Scalable
CPUs operate alongside powerful NVIDIA GPUs to process computationally heavy workloads, with samples run on their own cloud nodes.
Interoperable
Seamless, automated data transfer between technologies, EHR, LIMS, and interpretation tools for streamlined workflows.
Secure

HIPAA and GDPR compliant, ISO/IEC 27001, 27017 & 27018 certifications, and IVDR certified.*

*When used in Dx mode.

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SOPHiA DDM™ Platform

Experience the power of SOPHiA DDM™ for yourself with a free demo.

SOPHiA DDM™ Platform

Experience the power of SOPHiA DDM™ for yourself with a free demo.
Request a Demo

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise.

SOPHiA DDM™ Dx Hereditary Cancer Solution, SOPHiA DDM™ Dx RNAtarget Oncology Solution and SOPHiA DDM™ Dx Homologous Recombination Deficiency Solution are available as CE-IVD products for In Vitro Diagnostic Use in the European Economic Area (EEA), the United Kingdom and Switzerland. SOPHiA DDM™ Dx Myeloid Solution and SOPHiA DDM™ Dx Solid Tumor Solution are available as CE-IVD products for In Vitro Diagnostic Use in the EEA, the United Kingdom, Switzerland, and Israel. Information about products that may or may not be available in different countries and if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact us at support@sophiagenetics.com to obtain the appropriate product information for your country of residence.

All third-party trademarks listed by SOPHiA GENETICS remain the property of their respective owners. Unless specifically identified as such, SOPHiA GENETICS’ use of third-party trademarks does not indicate any relationship, sponsorship, or endorsement between SOPHiA GENETICS and the owners of these trademarks. Any references by SOPHiA GENETICS to third-party trademarks is to identify the corresponding third-party goods and/or services and shall be considered nominative fair use under the trademark law.

SOPHiA DDM™ Overview
Unlocking Insights, Transforming Healthcare
Learn About SOPHiA DDM™ 
SOPHiA DDM™ for Genomics

Oncology 

Rare and Inherited Disorders

Add-On Modules

SOPHiA DDM™ for Radiomics
Unlock entirely novel insights from your radiology images
Learn About SOPHiA DDM™ for Radiomics 
SOPHiA DDM™ for Multimodal
Explore new frontiers in biology and disease through novel insights
Learn About SOPHiA DDM™ for Multimodal
Professional Services
Accelerate breakthroughs with our tailored enablement services
Learn About our Professional Services